Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15101630 | 0.90 | ENPP2 (0.36) | CNR2TP53MTORPIK3C3 | |
| SCHEMBL10070415 | 0.90 | CNR2 (0.40) | CNR2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL368957 | 0.82 | TP53 (0.38) | CNR2TP53MTORLMNAPIK3C3 | |
| SCHEMBL369910 | 0.81 | TP53 (0.39) | CNR2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL10070934 | 0.80 | THRB (0.40) | CNR2TP53MAPTLMNAGAA | |
| SCHEMBL10070939 | 0.80 | LMNA (0.41) | CNR2TP53MAPTLMNAGAA | |
| SCHEMBL15101330 | 0.80 | ENPP2 (0.38) | CNR2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL10070403 | 0.79 | SMN1; SMN2 (0.39) | CNR2TP53MAPTLMNANPSR1 | |
| SCHEMBL367904 | 0.79 | KCNH2 (0.37) | CNR2GABRA1DRD4MTORKDM4E | |
| SCHEMBL15097386 | 0.79 | LRRK2 (0.42) | GABRA1DRD4MTORALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006680-A1 | 7, 9-NITROGEN RADICAL-4-OXO-4H-PYRIDO[L,2-A]PYRIMIDINE-2-CARBOXYLIC ACID BENZYLAMIDE ANTI-VIRALS | AVEXA LIMITED (AU) | 2012-01-19 | — | — | WO | disclosed |