SCHEMBL10070443

SCHEMBL10070443

CCOc1ccc(-c2nc(-c3ccc(-c4ccccc4)cc3)nc(-c3ccc(-c4ccccc4)cc3)n2)c(O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.57
CNR1 P21554 2/20 0.57
CNR2 P34972 2/20 0.57
GPR55 Q9Y2T6 2/20 0.57
GAA P10253 1/20 0.57
MAPK10 P53779 1/20 0.57
ESR1 P03372 2/20 0.48
RXRA P19793 1/20 0.48
RXRB P28702 1/20 0.48
MAPT P10636 4/20 0.47
GPR35 Q9HC97 1/20 0.47
KMT2A Q03164 6/20 0.46
MEN1 O00255 5/20 0.46
MAPK1 P28482 3/20 0.46
HTT P42858 2/20 0.46
TSHR P16473 3/20 0.46
ALOX15 P16050 3/20 0.46
ADORA3 P0DMS8 1/20 0.46
ADORA2A P29274 1/20 0.46
ADORA2B P29275 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1468002 0.97 LMNA (0.60) LMNACNR1CNR2GPR55GAA
SCHEMBL29375339 0.97 LMNA (0.60) LMNACNR1CNR2GPR55GAA
SCHEMBL13506418 0.92 LMNA (0.55) LMNACNR1CNR2GPR55GAA
SCHEMBL27863990 0.91 LMNA (0.54) LMNACNR1CNR2GPR55GAA
SCHEMBL5584373 0.89 MAPT (0.49) LMNACNR1CNR2GPR55GAA
SCHEMBL13249565 0.89 ALOX15 (0.48) LMNACNR1CNR2GPR55GAA
SCHEMBL9634541 0.87 LMNA (0.58) LMNACNR1CNR2GPR55GAA
SCHEMBL15297998 0.87 MAPT (0.60) LMNACNR1CNR2GPR55GAA
SCHEMBL4424332 0.87 CNR1 (0.51) LMNACNR1CNR2GPR55GAA
SCHEMBL13051346 0.87 TSHR (0.57) LMNACNR1CNR2GPR55GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120043480-A1 UV-DOSE INDICATOR FILMS BASF SE (DE) 2012-02-23 US disclosed