Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | IDH1 | O75874 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634226 | 0.97 | LMNA (0.56) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL9635984 | 0.92 | LMNA (0.54) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL9635558 | 0.91 | LMNA (0.53) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL1468002 | 0.90 | LMNA (0.60) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL29375339 | 0.90 | LMNA (0.60) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL9635991 | 0.88 | ADORA3 (0.50) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL10070443 | 0.87 | LMNA (0.57) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL9635572 | 0.87 | IDH1 (0.51) | LMNAGAAMAPK10IDH1MEN1 | |
| SCHEMBL13506418 | 0.85 | LMNA (0.55) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL9635563 | 0.83 | PTPN11 (0.54) | IDH1MEN1KMT2ANTSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280654-B1 | PROCESS FOR IMPROVING THE PHOTOCHEMICAL STABILITY OF DYEINGS ON FIBROUS POLYESTER MATERIALS | CIBA-GEIGY AG (CH) | 1992-05-13 | — | — | EP | disclosed |
| US-4895981-A | Using ultraviolet absorber | CIBA-GEIGY CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |