Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070076 | 0.92 | KIT (0.44) | HTR2BHSD11B1P2RY12TLR9TLR8 | |
| SCHEMBL10070539 | 0.92 | P2RY12 (0.47) | HTR2BHSD11B1P2RY12GPR119MGLL | |
| SCHEMBL10069714 | 0.90 | HSD11B1 (0.43) | HTR2BHSD11B1P2RY12TLR9TLR8 | |
| SCHEMBL10070106 | 0.89 | CPT1A (0.46) | HTR2BHSD11B1P2RY12TLR9TLR8 | |
| SCHEMBL10070517 | 0.89 | TRPV1 (0.42) | HTR2BHSD11B1P2RY12TLR9TLR8 | |
| SCHEMBL10070550 | 0.86 | CPT1A (0.40) | HTR2BHSD11B1P2RY12TLR9TLR8 | |
| SCHEMBL10070512 | 0.86 | HSD11B1 (0.42) | HSD11B1MEN1KMT2AALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL1653157 | 0.86 | HSD11B1 (0.42) | HSD11B1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL10070536 | 0.85 | CPT1A (0.46) | HTR2BHSD11B1P2RY12TLR9TLR8 | |
| SCHEMBL10070107 | 0.83 | AKT1 (0.42) | AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207199-B2 | Azole compound | ASTELLAS PHARMA INC. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20110118311-A1 | AZOLE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118311-A1 | AZOLE COMPOUND | FAAH, FAAH2, TRPV1 | HTR2B 2418/4885HSD11B1 2752/4885P2RY12 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.