SCHEMBL10071089

SCHEMBL10071089

C[C@@H](Cc1ccc(C(=O)c2ccccc2)cc1)CN1CCC[C@H]1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.46
ACE P12821 12/20 0.45
ACE2 Q9BYF1 5/20 0.45
MME P08473 1/20 0.43
MMEL1 Q495T6 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10071092 0.86 ADORA3 (0.50) F2ACENPSR1
SCHEMBL10071097 0.86 F2 (0.60) F2ACEACE2NPSR1
SCHEMBL10071095 0.82 ACE (0.52) ACE
SCHEMBL10447086 0.75 F2 (0.62) F2ACE
SCHEMBL10447085 0.75 F2 (0.62) F2ACE
SCHEMBL4696097 0.75 ACE (0.51) F2ACE
SCHEMBL15062947 0.75 ACE (0.51) F2ACE
SCHEMBL10082599 0.75 F2 (0.53) F2ACENPSR1
SCHEMBL10071088 0.73 ADORA3 (0.51) F2ACEMMEL1
SCHEMBL10752888 0.73 ACE (0.52) ACEACE2MMEMMEL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120045393-A1 LHRH-II PEPTIDE ANALOGS BRACCO IMAGING SPA (IT) 2012-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120045393-A1 LHRH-II PEPTIDE ANALOGS LHCGR, GNRHR, FSHR F2 4130/4885ACE 2838/4885ACE2 1470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.