Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10082599 | 0.89 | F2 (0.53) | ADORA3ADORA2AADORA2BADORA1KLK5 | |
| SCHEMBL10071088 | 0.87 | ADORA3 (0.51) | ADORA3ADORA2AADORA2BADORA1KLK5 | |
| SCHEMBL10071089 | 0.86 | F2 (0.46) | ACEF2NPSR1 | |
| SCHEMBL10071091 | 0.85 | ACE (0.57) | ADORA3ADORA2AADORA2BADORA1KLK5 | |
| SCHEMBL10071087 | 0.82 | ACE (0.51) | KLK5ACE | |
| SCHEMBL10082600 | 0.79 | DPP4 (0.52) | KLK5ACE | |
| SCHEMBL10082601 | 0.77 | ADORA3 (0.51) | ADORA3ADORA2AADORA2BADORA1KLK5 | |
| SCHEMBL16269854 | 0.76 | PARP1 (0.50) | ADORA3ADORA2AADORA2BADORA1ACE | |
| SCHEMBL13016622 | 0.76 | PARP1 (0.50) | ADORA3ADORA2AADORA2BADORA1ACE | |
| SCHEMBL28468245 | 0.76 | KMT2A (0.52) | ADORA3ADORA2AADORA2BADORA1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | BRACCO IMAGING SPA (IT) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | LHCGR, GNRHR, FSHR | ADORA3 3804/4885ADORA2A 4476/4885ADORA2B 4571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.