Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15223627 | 0.92 | KLK5 (0.55) | ACEKLK5ACE2CMA1 | |
| SCHEMBL10082600 | 0.89 | DPP4 (0.52) | ACEKLK5 | |
| SCHEMBL10071093 | 0.85 | ACE (0.64) | ACEKLK5ACE2PRSS1TMPRSS15 | |
| SCHEMBL10071092 | 0.82 | ADORA3 (0.50) | ACEKLK5 | |
| SCHEMBL15222270 | 0.81 | KLK5 (0.53) | ACEKLK5CMA1 | |
| SCHEMBL7380978 | 0.81 | ACE (0.52) | ACEACE2 | |
| SCHEMBL7321073 | 0.80 | DPP4 (0.58) | ACEKLK5PRSS1 | |
| SCHEMBL8366819 | 0.80 | DPP4 (0.58) | ACEKLK5PRSS1 | |
| SCHEMBL11124783 | 0.80 | ACE (0.79) | ACEACE2 | |
| SCHEMBL11124780 | 0.80 | ACE (0.79) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | BRACCO IMAGING SPA (IT) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | LHCGR, GNRHR, FSHR | ACE 2838/4885KLK5 151/4885ACE2 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.