Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20784863 | 0.84 | EPHX1 (0.39) | EPHX1POLBKDM4CSMN1; SMN2ALDH1A1 | |
| SCHEMBL6566836 | 0.84 | EPHX1 (0.57) | EPHX1POLBKDM4CHTTSMN1; SMN2 | |
| SCHEMBL10071176 | 0.82 | EPHX1 (0.60) | EPHX1KDM4CSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL21648769 | 0.81 | EPHX1 (0.47) | EPHX1POLBKDM4CHTTSMN1; SMN2 | |
| SCHEMBL618600 | 0.80 | EPHX1 (0.44) | EPHX1POLBKDM4CSMN1; SMN2KMT2A | |
| SCHEMBL14031260 | 0.77 | EPHX1 (0.52) | EPHX1POLBHTTSMN1; SMN2KMT2A | |
| SCHEMBL7823787 | 0.77 | EPHX1 (0.52) | EPHX1POLBHTTSMN1; SMN2KMT2A | |
| SCHEMBL1908722 | 0.77 | EPHX1 (0.42) | EPHX1KDM4CSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL6262428 | 0.77 | EPHX1 (0.42) | EPHX1KDM4CSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL16173925 | 0.77 | EPHX1 (0.47) | EPHX1POLBHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080107625-A1 | Inhibitors of Hepatitis C Virus | BRISTOL-MYERS SQUIBB COMPANY | 2008-05-08 | — | — | US | disclosed |
| US-7173004-B2 | Macrocyclic isoquinoline peptide inhibitors of hepatitis C virus | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080107625-A1 | Inhibitors of Hepatitis C Virus | HAVCR2, HCCS, VIP | EPHX1 2738/4885POLB 2106/4885KDM4C 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.