Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | ODC1 | P11926 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31239009 | 0.77 | LMNA (0.46) | PDE4DCA12CA1CA7CA9 | |
| SCHEMBL6795851 | 0.75 | ODC1 (0.46) | PDE4DCA12CA1CA7CA9 | |
| SCHEMBL10963021 | 0.74 | EP300 (0.48) | PDE4DKDM4ECASP1CASP7ALDH1A1 | |
| Prococene Ii SCHEMBL119925 | 0.74 | ODC1 (0.54) | ALDH1A1ODC1HIF1AEPAS1HPGD | |
| SCHEMBL15989623 | 0.73 | ALDH1A1 (0.47) | PDE4DCA12CA1CA7CA9 | |
| SCHEMBL15053101 | 0.73 | EP300 (0.49) | PDE4DKDM4ECASP1CASP7EP300 | |
| SCHEMBL5723520 | 0.71 | KDM4E (0.63) | PDE4DCA12CA1CA7CA9 | |
| SCHEMBL30589491 | 0.70 | PDE4D (1.00) | PDE4DCA12CA1CA7CA9 | |
| SCHEMBL11015336 | 0.70 | ODC1 (0.44) | PDE4DCA12CA1CA7CA9 | |
| SCHEMBL4454398 | 0.70 | ODC1 (0.50) | PDE4DCA12CA1CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120020972-A1 | ANTIBODIES RELATING TO PIVKA-II AND USES THEREOF | ABBOTT LABORATORIES (US) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120020972-A1 | ANTIBODIES RELATING TO PIVKA-II AND USES THEREOF | HDGF, HAVCR2, KLK3 | PDE4D 3670/4885CA12 11/4885CA1 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.