Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807522 | 0.87 | EGLN1 (0.46) | EGLN1APEX1ALDH1A1MAPTTDP1 | |
| SCHEMBL19683900 | 0.80 | MCL1 (0.36) | ALDH1A1TDP1LMNAKMT2ARECQL | |
| SCHEMBL6471153 | 0.78 | LDHA (0.47) | EGLN1APEX1ALDH1A1MAPTTDP1 | |
| SCHEMBL25372539 | 0.78 | FAAH (0.57) | APEX1ALDH1A1MAPTTDP1FAAH | |
| SCHEMBL25374861 | 0.78 | FAAH (0.57) | APEX1ALDH1A1MAPTTDP1FAAH | |
| SCHEMBL25373308 | 0.78 | FAAH (0.57) | APEX1ALDH1A1MAPTTDP1FAAH | |
| SCHEMBL2106440 | 0.78 | — | — | |
| SCHEMBL1329823 | 0.77 | EGLN1 (0.44) | EGLN1APEX1ALDH1A1MAPTTDP1 | |
| SCHEMBL1055886 | 0.77 | CTH (0.46) | EGLN1APEX1ALDH1A1MAPTTDP1 | |
| SCHEMBL19068037 | 0.76 | ECE1 (0.65) | EGLN1LMNAFAAHKDM4EECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202963-B2 | Tissue adhesives with modified elasticity | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-06-19 | — | — | US | disclosed |
| US-20110269916-A1 | TISSUE ADHESIVES WITH MODIFIED ELASTICITY | ACTAMAX SURGICAL MATERIALS, LLC | 2011-11-03 | — | — | US | disclosed |