Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12568561 | 0.86 | TSHR (0.64) | TSHRTP53EGLN1EGLN3LMNA | |
| SCHEMBL290398 | 0.80 | — | — | |
| SCHEMBL2780998 | 0.78 | TSHR (0.53) | TSHRTP53EGLN1EGLN3LMNA | |
| SCHEMBL2780997 | 0.78 | TSHR (0.53) | TSHRTP53EGLN1EGLN3LMNA | |
| SCHEMBL1225122 | 0.78 | TSHR (0.53) | TSHRTP53EGLN1EGLN3LMNA | |
| Fumaric Acid SCHEMBL1502680 | 0.76 | LMNA (0.77) | TSHRTP53EGLN1EGLN3LMNA | |
| Maleic Acid SCHEMBL6686451 | 0.76 | LMNA (0.77) | TSHRTP53EGLN1EGLN3LMNA | |
| Maleic Acid SCHEMBL31084206 | 0.76 | LMNA (0.77) | TSHRTP53EGLN1EGLN3LMNA | |
| Fumaric Acid SCHEMBL725567 | 0.76 | LMNA (0.77) | TSHRTP53EGLN1EGLN3LMNA | |
| Maleic Acid SCHEMBL725565 | 0.76 | LMNA (0.77) | TSHRTP53EGLN1EGLN3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202963-B2 | Tissue adhesives with modified elasticity | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-06-19 | — | — | US | disclosed |
| US-20110269916-A1 | TISSUE ADHESIVES WITH MODIFIED ELASTICITY | ACTAMAX SURGICAL MATERIALS, LLC | 2011-11-03 | — | — | US | disclosed |