⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660629 | 0.85 | LMNA (0.63) | — | |
| SCHEMBL23735526 | 0.77 | LMNA (0.55) | — | |
| SCHEMBL12026198 | 0.77 | — | — | |
| SCHEMBL43375 | 0.74 | — | — | |
| SCHEMBL4572119 | 0.74 | HDAC2 (0.57) | — | |
| SCHEMBL2754572 | 0.74 | — | — | |
| SCHEMBL93970 | 0.74 | — | — | |
| SCHEMBL671686 | 0.74 | — | — | |
| SCHEMBL7753090 | 0.73 | LMNA (0.57) | — | |
| SCHEMBL5909180 | 0.73 | LMNA (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202963-B2 | Tissue adhesives with modified elasticity | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-06-19 | — | — | US | disclosed |
| US-20110269916-A1 | TISSUE ADHESIVES WITH MODIFIED ELASTICITY | ACTAMAX SURGICAL MATERIALS, LLC | 2011-11-03 | — | — | US | disclosed |