Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995402 | 1.00 | LMNA (0.56) | LMNATSHRTHRBDNM1LCK | |
| SCHEMBL1990689 | 1.00 | LMNA (0.56) | LMNATSHRTHRBDNM1LCK | |
| SCHEMBL1995024 | 1.00 | LMNA (0.56) | LMNATSHRTHRBDNM1LCK | |
| SCHEMBL19568233 | 1.00 | LMNA (0.56) | LMNATSHRTHRBDNM1LCK | |
| SCHEMBL1437436 | 1.00 | LMNA (0.56) | LMNATSHRTHRBDNM1LCK | |
| SCHEMBL23421276 | 1.00 | LMNA (0.56) | LMNATSHRTHRBDNM1LCK | |
| SCHEMBL17188257 | 1.00 | LMNA (0.56) | LMNATSHRTHRBDNM1LCK | |
| SCHEMBL13165929 | 1.00 | LMNA (0.56) | LMNATSHRTHRBDNM1LCK | |
| SCHEMBL324583 | 1.00 | LMNA (0.56) | LMNATSHRTHRBDNM1LCK | |
| SCHEMBL1989574 | 1.00 | LMNA (0.56) | LMNATSHRTHRBDNM1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120116050-A1 | PYRENE-BASED POLYMERS FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) | TECHNISCHE UNIVERSITAET GRAZ (AT) | 2012-05-10 | — | — | US | disclosed |
| US-20120116050-A1 | PYRENE-BASED POLYMERS FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) | TECHNISCHE UNIVERSITAET GRAZ (AT) | 2012-05-10 | — | — | US | disclosed |
| WO-2010145726-A1 | PYRENE-BASED POLYMERS FOR ORGANIC LIGHT EMITTING DIODES (OLEDS ) | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116050-A1 | PYRENE-BASED POLYMERS FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) | NR1H2, NR1H3, OPRD1 | LMNA 2556/4885TSHR 874/4885THRB 1791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.