SCHEMBL1990689

SCHEMBL1990689

CCCCCCCC(CBr)CCCCC

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.44
DNM1 Q05193 2/20 0.43
LCK P06239 1/20 0.43
PPARD Q03181 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
OPRM1 P35372 1/20 0.42
PLA2G1B P04054 1/20 0.41
PLA2G2A P14555 1/20 0.41
GPR84 Q9NQS5 3/20 0.39
FDPS P14324 3/20 0.39
SPHK1 Q9NYA1 1/20 0.39
FFAR1 O14842 1/20 0.39
ZDHHC7 Q9NXF8 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1995402 1.00 LMNA (0.56) LMNATSHRTHRBDNM1LCK
SCHEMBL10071656 1.00 LMNA (0.56) LMNATSHRTHRBDNM1LCK
SCHEMBL1995024 1.00 LMNA (0.56) LMNATSHRTHRBDNM1LCK
SCHEMBL19568233 1.00 LMNA (0.56) LMNATSHRTHRBDNM1LCK
SCHEMBL1437436 1.00 LMNA (0.56) LMNATSHRTHRBDNM1LCK
SCHEMBL23421276 1.00 LMNA (0.56) LMNATSHRTHRBDNM1LCK
SCHEMBL17188257 1.00 LMNA (0.56) LMNATSHRTHRBDNM1LCK
SCHEMBL13165929 1.00 LMNA (0.56) LMNATSHRTHRBDNM1LCK
SCHEMBL324583 1.00 LMNA (0.56) LMNATSHRTHRBDNM1LCK
SCHEMBL1989574 1.00 LMNA (0.56) LMNATSHRTHRBDNM1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9309481-B2 Lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2016-04-12 US disclosed
US-9074158-B2 Detergent-dispersant, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2015-07-07 US disclosed
US-8853139-B2 Detergent-dispersant, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2014-10-07 US disclosed
US-20140296115-A1 DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2014-10-02 US disclosed
US-8841242-B2 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2014-09-23 US disclosed
US-20130045904-A1 DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IWASAKI JUNYA (JP) 2013-02-21 US disclosed
EP-2546324-A1 LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2013-01-16 EP disclosed
US-20130005624-A1 LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2013-01-03 US disclosed
EP-2520638-A1 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2012-11-07 EP disclosed
US-20110152145-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2011-06-23 US disclosed
US-20100184982-A1 DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD (JP) 2010-07-22 US disclosed
EP-2177594-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-04-21 EP disclosed
EP-2161324-A1 DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184982-A1 DETERGENT-DISPERSANT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION DSC1, DSP, CDC73 LMNA 3367/4885TSHR 2932/4885THRB 4203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.