Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.85 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.78 |
| ▸ | SPR | P35270 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-P-Coumaroyl Serotonin SCHEMBL29594565 | 0.92 | MAOB (1.00) | MAOBPTGS2SPRKDM4EALDH1A1 | |
| N-P-Coumaroyl Serotonin SCHEMBL471922 | 0.92 | MAOB (1.00) | MAOBPTGS2SPRKDM4EALDH1A1 | |
| N-P-Coumaroyl Serotonin SCHEMBL471921 | 0.92 | MAOB (1.00) | MAOBPTGS2SPRKDM4EALDH1A1 | |
| SCHEMBL10070991 | 0.91 | PTGS2 (0.82) | MAOBPTGS2SPRKDM4EALDH1A1 | |
| N-Cinnamoyl Serotonin SCHEMBL31276875 | 0.90 | MAOB (0.87) | MAOBPTGS2SPRKDM4EALDH1A1 | |
| N-Cinnamoyl Serotonin SCHEMBL471939 | 0.90 | MAOB (0.87) | MAOBPTGS2SPRKDM4EALDH1A1 | |
| N-Cinnamoyl Serotonin SCHEMBL471940 | 0.90 | MAOB (0.87) | MAOBPTGS2SPRKDM4EALDH1A1 | |
| N-Cinnamoyl Serotonin SCHEMBL29593853 | 0.90 | MAOB (0.87) | MAOBPTGS2SPRKDM4EALDH1A1 | |
| N-Sinapoyl Serotonin SCHEMBL803240 | 0.89 | MAOB (0.74) | MAOBPTGS2SPRKDM4EALDH1A1 | |
| N-Caffeoylserotonin SCHEMBL30039282 | 0.88 | PTGS2 (1.00) | MAOBPTGS2SPRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9295624-B2 | Amide derivative and whitening agent | AJINOMOTO CO., INC. (JP) | 2016-03-29 | — | — | US | disclosed |
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC. (JP) | 2014-09-11 | — | — | US | disclosed |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2412701-A1 | NOVEL AMIDE DERIVATIVE AND SKIN WHITENING AGENT | Ajinomoto Co., Inc. (JP) | 2012-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | MAOB 416/4885PTGS2 2191/4885SPR 3569/4885 |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | MAOB 416/4885PTGS2 2191/4885SPR 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.