N-Cinnamoyl Serotonin

N-Cinnamoyl Serotonin

SCHEMBL471940

O=C(C=Cc1ccccc1)NCCc1c[nH]c2ccc(O)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.87
PTGS2 P35354 3/20 0.77
SPR P35270 2/20 0.62
KDM4E B2RXH2 1/20 0.62
ALDH1A1 P00352 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2D6 P10635 1/20 0.62
MAPT P10636 1/20 0.62
IDO1 P14902 1/20 0.62
HPGD P15428 1/20 0.62
BLM P54132 1/20 0.62
NOTUM Q6P988 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
BACE1 P56817 1/20 0.62
TRPV1 Q8NER1 3/20 0.61
PTGS1 P23219 2/20 0.61
SIRT2 Q8IXJ6 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Cinnamoyl Serotonin SCHEMBL29593853 1.00 MAOB (0.87) MAOBPTGS2SPRKDM4EALDH1A1
N-Cinnamoyl Serotonin SCHEMBL31276875 1.00 MAOB (0.87) MAOBPTGS2SPRKDM4EALDH1A1
N-Cinnamoyl Serotonin SCHEMBL471939 1.00 MAOB (0.87) MAOBPTGS2SPRKDM4EALDH1A1
N-P-Coumaroyl Serotonin SCHEMBL471922 0.93 MAOB (1.00) MAOBPTGS2SPRKDM4EALDH1A1
N-P-Coumaroyl Serotonin SCHEMBL29594565 0.93 MAOB (1.00) MAOBPTGS2SPRKDM4EALDH1A1
N-P-Coumaroyl Serotonin SCHEMBL471921 0.93 MAOB (1.00) MAOBPTGS2SPRKDM4EALDH1A1
SCHEMBL10071696 0.90 MAOB (0.85) MAOBPTGS2SPRKDM4EALDH1A1
SCHEMBL10070991 0.88 PTGS2 (0.82) MAOBPTGS2SPRKDM4EALDH1A1
SCHEMBL27488695 0.87 SIRT2 (0.74) MAOBPTGS2ALDH1A1CYP1A2MAPT
SCHEMBL27488694 0.87 SIRT2 (0.74) MAOBPTGS2ALDH1A1CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118178491-A Safflower extract and preparation method and application thereof 中南民族大学 2024-06-14 CN claimed
CN-118178491-B Safflower extract and preparation method and application thereof 中南民族大学 2026-05-19 CN disclosed
CN-118178491-B Safflower extract and preparation method and application thereof 中南民族大学 2026-05-19 CN disclosed
CN-118879402-A Preparation method of safflower seed oil rich in benzoyl-5-hydroxytryptamine 河南工业大学 2024-11-01 CN disclosed
CN-118178491-A Safflower extract and preparation method and application thereof 中南民族大学 2024-06-14 CN disclosed
CN-118178491-A Safflower extract and preparation method and application thereof 中南民族大学 2024-06-14 CN disclosed
US-9295624-B2 Amide derivative and whitening agent AJINOMOTO CO., INC. (JP) 2016-03-29 US disclosed
EP-2412701-B1 NOVEL AMIDE DERIVATIVE AND SKIN WHITENING AGENT AJINOMOTO KK (JP) 2015-08-12 EP disclosed
US-20140255327-A1 NOVEL AMIDE DERIVATIVE AND WHITENING AGENT AJINOMOTO CO. INC. (JP) 2014-09-11 US disclosed
US-20120070395-A1 NOVEL AMIDE DERIVATIVE AND WHITENING AGENT AJINOMOTO CO. INC (JP) 2012-03-22 US disclosed
EP-2412701-A1 NOVEL AMIDE DERIVATIVE AND SKIN WHITENING AGENT Ajinomoto Co., Inc. (JP) 2012-02-01 EP disclosed
CN-101323585-B Enrichment and purification method of benzene acryloyl 5-hydroxytryptamine compound in safflower seed UNIV JIANGNAN 2010-08-25 CN disclosed
CN-100526296-C Method for purifying and enriching benzene acryloyl 5- hydroxytryptamine derivant in safflower seed UNIV JIANGNAN (CN) 2009-08-12 CN disclosed
CN-100526296-C Method for purifying and enriching benzene acryloyl 5- hydroxytryptamine derivant in safflower seed UNIV JIANGNAN (CN) 2009-08-12 CN disclosed
CN-101323585-A Enrichment and purification method of benzene acryloyl 5-hydroxytryptamine compound in safflower seed UNIV JIANGNAN (CN) 2008-12-17 CN disclosed
CN-101130516-A Method for purifying and enriching benzene acryloyl 5- hydroxytryptamine derivant in safflower seed UNIV JIANGNAN (CN) 2008-02-27 CN disclosed
CN-101130516-A Method for purifying and enriching benzene acryloyl 5- hydroxytryptamine derivant in safflower seed UNIV JIANGNAN (CN) 2008-02-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140255327-A1 NOVEL AMIDE DERIVATIVE AND WHITENING AGENT CUTA, NAT1, TYR MAOB 416/4885PTGS2 2191/4885SPR 3569/4885
US-20120070395-A1 NOVEL AMIDE DERIVATIVE AND WHITENING AGENT CUTA, NAT1, TYR MAOB 416/4885PTGS2 2191/4885SPR 3569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.