SCHEMBL10071737

SCHEMBL10071737

O=C(Nc1ccc(O)cc1)c1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 3/20 0.56
SNCA P37840 1/20 0.49
NQO2 P16083 2/20 0.46
PTPN1 P18031 4/20 0.45
XDH P47989 1/20 0.44
AURKA O14965 1/20 0.43
MIF P14174 1/20 0.43
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43
TRPV1 Q8NER1 2/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125596 1.00 DEGS1 (0.56) DEGS1SNCANQO2PTPN1XDH
SCHEMBL10167294 0.91 DEGS1 (0.50) DEGS1SNCANQO2AURKAKDM4E
SCHEMBL19027324 0.89 DEGS1 (0.48) DEGS1SNCANQO2PTPN1XDH
SCHEMBL12196214 0.88 RAB9A (0.59) KDM4ETRPV1MAPT
SCHEMBL12922922 0.87 PTPN1 (0.61) DEGS1PTPN1KDM4EPOLB
SCHEMBL460764 0.84 RAB9A (0.62) SNCAXDHKDM4EPOLBMAPT
SCHEMBL13578708 0.82 XDH (0.60) XDHKDM4ETRPV1MAPT
SCHEMBL8956401 0.82 KMT2A (0.50) XDHKDM4EPOLBMAPT
SCHEMBL12670423 0.82 RAB9A (0.55) KDM4ETRPV1MAPT
SCHEMBL8607879 0.82 MEN1 (0.48) POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092872-B2 Optical film, antireflection film, and polarizing plate and display device using the same FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-8092872-B2 Optical film, antireflection film, and polarizing plate and display device using the same FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-20080131674-A1 OPTICAL FILM, ANTIREFLECTION FILM, AND POLARIZING PLATE AND DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-06-05 US disclosed
US-20080131674-A1 OPTICAL FILM, ANTIREFLECTION FILM, AND POLARIZING PLATE AND DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-06-05 US disclosed