SCHEMBL10167294

SCHEMBL10167294

Cc1nc(-c2ccc(NC(=O)c3ccc(O)cc3)cc2)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 2/20 0.50
SNCA P37840 1/20 0.44
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
TRPV1 Q8NER1 6/20 0.43
TP53 P04637 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
NQO2 P16083 2/20 0.41
MEN1 O00255 1/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
AURKA O14965 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12670423 0.91 RAB9A (0.55) NPC1RAB9ATRPV1TP53KDM4E
SCHEMBL10071737 0.91 DEGS1 (0.56) DEGS1SNCATRPV1KDM4EMAPT
SCHEMBL125596 0.91 DEGS1 (0.56) DEGS1SNCATRPV1KDM4EMAPT
SCHEMBL12196214 0.85 RAB9A (0.59) NPC1RAB9ATRPV1TP53KDM4E
SCHEMBL19027324 0.83 DEGS1 (0.48) DEGS1SNCATRPV1MAPTNQO2
SCHEMBL10167298 0.81 LMNA (0.54) NPC1RAB9ATP53KDM4EALDH1A1
SCHEMBL12922922 0.79 PTPN1 (0.61) DEGS1NPC1RAB9AKDM4EALDH1A1
SCHEMBL460764 0.79 RAB9A (0.62) SNCANPC1RAB9ATP53KDM4E
SCHEMBL13578708 0.77 XDH (0.60) NPC1RAB9ATRPV1TP53KDM4E
SCHEMBL8956401 0.77 KMT2A (0.50) NPC1RAB9ATP53KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124224-B2 Antireflection laminate, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-7939576-B2 Antireflection film, process of producing the same, and polarizing plate and display device including the same FUJIFILM CORPORATION (JP) 2011-05-10 US disclosed
US-20080239486-A1 ANTIREFLECTION LAMINATE, POLARIZING PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed