Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918542 | 0.82 | TSHR (0.71) | TSHRLMNAALDH1A1ALOX15CYP1A2 | |
| SCHEMBL1491377 | 0.80 | TSHR (0.59) | TSHRLMNAALDH1A1ALOX15CYP1A2 | |
| SCHEMBL94845 | 0.80 | TSHR (0.69) | TSHRLMNAALDH1A1ALOX15CYP1A2 | |
| SCHEMBL8713184 | 0.80 | TSHR (0.69) | TSHRLMNAALDH1A1ALOX15CYP1A2 | |
| SCHEMBL13983018 | 0.79 | TSHR (0.57) | TSHRLMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5261537 | 0.79 | TSHR (0.57) | TSHRLMNAALDH1A1ALOX15CYP1A2 | |
| SCHEMBL17230076 | 0.79 | GRIN2B (0.48) | TSHRLMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL189560 | 0.78 | TSHR (0.67) | TSHRLMNAALDH1A1ALOX15CYP1A2 | |
| SCHEMBL356063 | 0.78 | TSHR (1.00) | TSHRLMNAALDH1A1ALOX15CYP1A2 | |
| SCHEMBL8245788 | 0.78 | TSHR (0.67) | TSHRLMNAALDH1A1ALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8945515-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2015-02-03 | — | — | US | disclosed |
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, PPOX, PRDX5 | TSHR 4483/4885LMNA 88/4885ALDH1A1 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.