SCHEMBL10072216

SCHEMBL10072216

COC(=O)OCc1ccc(N(c2ccc(COC(=O)OC)cc2)c2ccc(OC(=O)OC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.47
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 2/20 0.44
NPC1 O15118 2/20 0.44
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HSD17B10 Q99714 2/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
ATM Q13315 1/20 0.39
HTT P42858 2/20 0.38
KMT2A Q03164 4/20 0.38
MAPT P10636 4/20 0.38
MEN1 O00255 3/20 0.38
LMNA P02545 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
NOX1 Q9Y5S8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279306 0.91 ALDH1A1 (0.51) ALDH1A1KDM4ENPC1HPGDSMN1; SMN2
SCHEMBL279175 0.85 KMT2A (0.47) ALDH1A1KDM4ENPC1HPGDSMN1; SMN2
SCHEMBL279194 0.84 ALDH1A1 (0.47) ALDH1A1KDM4ENPC1HPGDSMN1; SMN2
SCHEMBL279338 0.84 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1HPGDSMN1; SMN2
SCHEMBL279308 0.84 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1HPGDSMN1; SMN2
SCHEMBL15080652 0.81 ALDH1A1 (0.43) ALDH1A1KDM4ENPC1HPGDSMN1; SMN2
SCHEMBL279498 0.81 RAB9A (0.48) ALDH1A1KDM4ENPC1HPGDSMN1; SMN2
SCHEMBL12316661 0.81 NPC1 (0.43) ALDH1A1KDM4ENPC1HPGDSMN1; SMN2
SCHEMBL279591 0.81 RAB9A (0.48) ALDH1A1KDM4ENPC1HPGDSMN1; SMN2
SCHEMBL279026 0.80 KMT2A (0.48) HTR2AALDH1A1HPGDHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 US disclosed