SCHEMBL279175

SCHEMBL279175

COC(=O)Oc1ccc(N(c2ccc(OC(=O)OC)cc2)c2ccc(OC(=O)OC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.47
MEN1 O00255 4/20 0.47
MAPT P10636 4/20 0.44
HSD17B10 Q99714 3/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 2/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP14 P50281 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NPC1 O15118 1/20 0.40
TP53 P04637 1/20 0.40
ESR2 Q92731 1/20 0.40
NOX1 Q9Y5S8 1/20 0.40
OPRK1 P41145 1/20 0.39
KDM4E B2RXH2 2/20 0.39
ELANE P08246 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279599 0.93 KMT2A (0.48) KMT2AMEN1MAPTHSD17B10ALDH1A1
SCHEMBL279173 0.93 KMT2A (0.48) KMT2AMEN1MAPTHSD17B10ALDH1A1
SCHEMBL676909 0.87 KMT2A (0.58) KMT2AMEN1MAPTHSD17B10ALDH1A1
SCHEMBL9915237 0.86 KMT2A (0.46) KMT2AMEN1MAPTHSD17B10ALDH1A1
SCHEMBL10072216 0.85 HTR2A (0.47) KMT2AMEN1MAPTHSD17B10ALDH1A1
SCHEMBL6936328 0.80 MMP2 (0.55) KMT2AMEN1MAPTHSD17B10ALDH1A1
SCHEMBL8779173 0.80 KMT2A (0.52) KMT2AMEN1MAPTHSD17B10ALDH1A1
SCHEMBL697317 0.80 CA1 (0.56) KMT2AMEN1ALDH1A1LMNAHTT
SCHEMBL8830906 0.78 KMT2A (0.50) KMT2AMEN1MAPTHSD17B10ALDH1A1
SCHEMBL1598492 0.78 LMNA (0.61) KMT2AMEN1MAPTHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475982-B2 Charge-transporting compound, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2013-07-02 US disclosed
US-8475982-B2 Charge-transporting compound, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2013-07-02 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed