⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728634 | 0.82 | CYP2C19 (0.32) | — | |
| SCHEMBL19231488 | 0.81 | — | — | |
| SCHEMBL14638747 | 0.80 | NPSR1 (0.38) | — | |
| SCHEMBL21738681 | 0.80 | — | — | |
| SCHEMBL18653337 | 0.80 | — | — | |
| SCHEMBL23366120 | 0.80 | — | — | |
| SCHEMBL18087338 | 0.76 | CYP2C19 (0.33) | — | |
| SCHEMBL17662468 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL16670401 | 0.74 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL18084533 | 0.73 | KDM4E (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323344-A1 | POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER | ARES CAPITAL CORPORATION, AS AGENT | 2023-10-12 | — | — | US | disclosed |
| US-20230127659-A1 | ANTIBODY-CONJUGATES WITH IMPROVED THERAPEUTIC INDEX FOR TARGETING HER2 TUMOURS AND METHOD FOR IMPROVING THERAPEUTIC INDEX OF ANTIBODY-CONJUGATES | SYNAFFIX B.V. (NL) | 2023-04-27 | — | — | US | disclosed |
| EP-4101930-A1 | POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION | ModernaTX, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| US-11192918-B2 | Multicyclic peptides and methods for their preparation | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2021-12-07 | — | — | US | disclosed |
| US-20200239516-A1 | Multicyclic Peptides and Methods for Their Preparation | UNIVERSITEIT VAN AMSTERDAM (NL) | 2020-07-30 | — | — | US | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| WO-2017049275-A2 | POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION | MODERNA THERAPEUTICS, INC. (US) | 2017-03-23 | — | — | WO | disclosed |
| WO-2012057624-A1 | NOVEL BICYCLIC PEPTIDE MIMETICS | PEPSCAN SYSTEMS B.V. (NL) | 2012-05-03 | — | — | WO | disclosed |