SCHEMBL14638747

SCHEMBL14638747

COC(=O)C1(F)C#CCCCCC1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.38
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10073174 0.82 ALDH1A1 (0.33) NPSR1MEN1CYP3A4KMT2AALDH1A1
SCHEMBL10072896 0.80
SCHEMBL16670401 0.80 SMN1; SMN2 (0.32)
SCHEMBL2728634 0.78 CYP2C19 (0.32)
SCHEMBL19231488 0.77
SCHEMBL23366120 0.76
SCHEMBL18653337 0.76
SCHEMBL21738681 0.76
SCHEMBL18087338 0.76 CYP2C19 (0.33) L3MBTL1
SCHEMBL17662468 0.76 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4377363-A1 FUNCTIONALISATION OF CARBOXYMETHYLCELLULOSE The University of Manchester (GB) 2024-06-05 EP disclosed
WO-2023006909-A1 FUNCTIONALISATION OF CARBOXYMETHYLCELLULOSE THE UNIVERSITY OF MANCHESTER (GB) 2023-02-02 WO disclosed
US-20230035986-A1 NOVEL CROSSLINKED ALGINIC ACID MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2023-02-02 US disclosed
US-20210221835-A1 CARBON-MONOXIDE-RELEASING MOLECULES AND THERAPEUTIC APPLICATIONS THEREOF GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2021-07-22 US disclosed
US-10751344-B2 Carbon monoxide-releasing molecules for therapeutic applications and methods for the preparation and use thereof GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2020-08-25 US disclosed
US-20190350937-A1 CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS FOR THE PREPARATION AND USE THEREOF GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2019-11-21 US disclosed
US-10300069-B2 Carbon monoxide-releasing molecules for therapeutic applications and methods of making and using thereof GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2019-05-28 US disclosed
WO-2018093924-A1 CARBON MONOXIDE-RELEASING MOLECULES AND THERAPEUTIC APPLICATIONS THEREOF GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2018-05-24 WO disclosed
US-20170128456-A1 CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC, (US) 2017-05-11 US disclosed
US-20170128456-A1 CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC, (US) 2017-05-11 US disclosed
US-9476883-B2 Cellular recognition conjugates and methods of use for the histological analysis of cancer tissue using MALDI-MS imaging GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) 2016-10-25 US disclosed
US-9476883-B2 Cellular recognition conjugates and methods of use for the histological analysis of cancer tissue using MALDI-MS imaging GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) 2016-10-25 US disclosed
US-9476883-B2 Cellular recognition conjugates and methods of use for the histological analysis of cancer tissue using MALDI-MS imaging GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) 2016-10-25 US disclosed
WO-2015191616-A1 CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2015-12-17 WO disclosed
US-20140315220-A1 CELLULAR RECOGNITION CONJUGATES AND METHODS OF USE FOR THE HISTOLOGICAL ANALYSIS OF CANCER TISSUE USING MALDI-MS IMAGING GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) 2014-10-23 US disclosed
US-20140315220-A1 CELLULAR RECOGNITION CONJUGATES AND METHODS OF USE FOR THE HISTOLOGICAL ANALYSIS OF CANCER TISSUE USING MALDI-MS IMAGING GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) 2014-10-23 US disclosed
US-20140315220-A1 CELLULAR RECOGNITION CONJUGATES AND METHODS OF USE FOR THE HISTOLOGICAL ANALYSIS OF CANCER TISSUE USING MALDI-MS IMAGING GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) 2014-10-23 US disclosed
EP-2734043-A1 CELLULAR RECOGNITION CONJUGATES AND METHODS OF USE FOR THE HISTOLOGICAL ANALYSIS OF CANCER TISSUE USING MALDI-MS IMAGING Georgia State University Research Foundation, Inc. (US) 2014-05-28 EP disclosed
WO-2013013130-A1 CELLULAR RECOGNITION CONJUGATES AND METHODS OF USE FOR THE HISTOLOGICAL ANALYSIS OF CANCER TISSUE USING MALDI-MS IMAGING GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) 2013-01-24 WO disclosed
WO-2013013130-A1 CELLULAR RECOGNITION CONJUGATES AND METHODS OF USE FOR THE HISTOLOGICAL ANALYSIS OF CANCER TISSUE USING MALDI-MS IMAGING GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) 2013-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170128456-A1 CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF MB, CYC1, COX15 NPSR1 874/4885MAPT 3963/4885MEN1 2152/4885
US-20210221835-A1 CARBON-MONOXIDE-RELEASING MOLECULES AND THERAPEUTIC APPLICATIONS THEREOF MB, HMOX1, CYC1 NPSR1 874/4885MAPT 3633/4885MEN1 2719/4885
US-10751344-B2 Carbon monoxide-releasing molecules for therapeutic applications and methods for the preparation and use thereof MB, CYC1, HMOX1 NPSR1 978/4885MAPT 3624/4885MEN1 2461/4885
US-10300069-B2 Carbon monoxide-releasing molecules for therapeutic applications and methods of making and using thereof MB, CYC1, COX15 NPSR1 874/4885MAPT 3963/4885MEN1 2152/4885
US-20190350937-A1 CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS FOR THE PREPARATION AND USE THEREOF MB, CYC1, HMOX1 NPSR1 978/4885MAPT 3624/4885MEN1 2461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.