SCHEMBL16670401

SCHEMBL16670401

O=C(Oc1c(F)c(F)c(F)c(F)c1F)C1(F)C#CCCCCC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14638747 0.80 NPSR1 (0.38)
SCHEMBL10073174 0.76 ALDH1A1 (0.33) SMN1; SMN2
SCHEMBL10072896 0.74
SCHEMBL24796109 0.72 SMN1; SMN2 (0.36) SMN1; SMN2
SCHEMBL2728634 0.72 CYP2C19 (0.32)
SCHEMBL19231488 0.71
SCHEMBL21738681 0.70
SCHEMBL18653337 0.70
SCHEMBL23366120 0.70
SCHEMBL18087338 0.67 CYP2C19 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3922269-A1 EXTENDED RELEASE CONJUGATES OF EXENATIDE ANALOGS Prolynx LLC (US) 2021-12-15 EP disclosed
US-20200164083-A1 EXTENDED RELEASE CONJUGATES OF EXENATIDE ANALOGS PROLYNX LLC (US) 2020-05-28 US disclosed
US-10413594-B2 Conjugates of somatostatin analogues PROLYNX LLC (US) 2019-09-17 US disclosed
CN-109414469-A The sustained release conjugate of Exenatide analog 普罗林科斯有限责任公司 2019-03-01 CN disclosed
EP-3429608-A1 EXTENDED RELEASE CONJUGATES OF EXENATIDE ANALOGS Prolynx LLC (US) 2019-01-23 EP disclosed
US-20180296648-A1 CONJUGATES OF SOMATOSTATIN ANALOGUES PROLYNX LLC (US) 2018-10-18 US disclosed
US-10086049-B2 Conjugates of somatostatin analogues PROLYNX LLC (US) 2018-10-02 US disclosed
WO-2017161174-A1 EXTENDED RELEASE CONJUGATES OF EXENATIDE ANALOGS PROLYNX LLC (US) 2017-09-21 WO disclosed
US-20160271227-A1 CONJUGATES OF SOMATOSTATIN ANALOGUES PROLYNX LLC (US) 2016-09-22 US disclosed
EP-3060230-A1 CONJUGATES OF SOMATOSTATIN AND ITS ANALOGS Prolynx LLC (US) 2016-08-31 EP disclosed
WO-2015061503-A1 CONJUGATES OF SOMATOSTATIN AND ITS ANALOGS PROLYNX LLC (US) 2015-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200164083-A1 EXTENDED RELEASE CONJUGATES OF EXENATIDE ANALOGS GLP1R, IAPP, GIPR SMN1; SMN2 213/4885
US-20180296648-A1 CONJUGATES OF SOMATOSTATIN ANALOGUES SSTR4, SSTR3, SSTR2 SMN1; SMN2 993/4885
US-20160271227-A1 CONJUGATES OF SOMATOSTATIN ANALOGUES SSTR4, SSTR3, SSTR2 SMN1; SMN2 993/4885
US-10413594-B2 Conjugates of somatostatin analogues SSTR4, SSTR3, SSTR2 SMN1; SMN2 993/4885
US-10086049-B2 Conjugates of somatostatin analogues SSTR4, SSTR3, SSTR2 SMN1; SMN2 993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.