Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688555 | 1.00 | GAA (0.43) | GAAHTR1AHTR1DHTR1BLMNA | |
| SCHEMBL13343069 | 0.82 | LMNA (0.41) | GAALMNAALDH1A1DRD2DRD3 | |
| SCHEMBL688622 | 0.82 | LMNA (0.41) | GAALMNAALDH1A1DRD2DRD3 | |
| SCHEMBL10073567 | 0.77 | LMNA (0.43) | LMNAALDH1A1HTTKMT2APPARG | |
| SCHEMBL688256 | 0.77 | LMNA (0.43) | LMNAALDH1A1HTTKMT2APPARG | |
| SCHEMBL687300 | 0.77 | HTR1A (0.39) | HTR1AHTR1DHTR1BLMNADRD2 | |
| SCHEMBL10072501 | 0.76 | GAA (0.44) | GAALMNAALDH1A1CA12CA2 | |
| SCHEMBL687784 | 0.76 | GAA (0.44) | GAALMNAALDH1A1CA12CA2 | |
| SCHEMBL687288 | 0.75 | CXCR2 (0.44) | GAAHTR1AHTR1DHTR1BALDH1A1 | |
| SCHEMBL6456001 | 0.75 | HTR1A (0.42) | GAAHTR1AHTR1DHTR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606248-B1 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE SPA (IT) | 2012-02-29 | — | — | EP | disclosed |
| US-7737139-B2 | Sulfonic acids, their derivatives and pharmaceutical compositions containing them | DOMPE PHA.R.MA S.P.A. (IT) | 2010-06-15 | — | — | US | disclosed |