SCHEMBL1007351

SCHEMBL1007351

C=C(CCCOC(=O)C(C)(C)Br)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.36
TET2 Q6N021 1/20 0.35
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11434414 0.86 TBXAS1 (0.34) TBXAS1TET2
SCHEMBL13010132 0.82 TSHR (0.34) POLBGAANPSR1
SCHEMBL1803764 0.79 POLB (0.39) POLBGAANPSR1
SCHEMBL37083 0.79 POLB (0.39) POLBGAANPSR1
SCHEMBL8652621 0.79 TBXAS1 (0.31) TBXAS1
SCHEMBL8653034 0.79 TET2 (0.35) TBXAS1TET2
SCHEMBL30719950 0.78 TET2 (0.39) TET2
SCHEMBL28902649 0.77 NAAA (0.40) POLBGAANPSR1
SCHEMBL651971 0.77 NAAA (0.40) POLBGAANPSR1
SCHEMBL2632255 0.77 HSD17B10 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3042645-B2 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2025-03-12 EP claimed
EP-3042645-B1 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2022-04-27 EP claimed
WO-2016110571-A1 DENTAL COMPOSITES WITH IMPROVED STORAGE STABILITY IVOCLAR VIVADENT AG (LI) 2016-07-14 WO claimed
EP-3042645-A1 Dental composites with improved storage stability Ivoclar Vivadent AG (LI) 2016-07-13 EP claimed
EP-3042645-B2 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2025-03-12 EP disclosed
EP-3042645-B1 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2022-04-27 EP disclosed
EP-3233934-B1 REACTION RESIN COMPOSITION AND ITS USE HILTI AG (LI) 2021-10-20 EP disclosed
EP-3019573-B1 REACTION RESIN COMPOSITION AND ITS USE HILTI AG (LI) 2017-08-23 EP disclosed
EP-3184499-A1 REACTION RESIN COMPOSITION, MULTI-COMPONENT SYSTEM AND ITS USE HILTI Aktiengesellschaft (LI) 2017-06-28 EP disclosed
WO-2016110571-A1 DENTAL COMPOSITES WITH IMPROVED STORAGE STABILITY IVOCLAR VIVADENT AG (LI) 2016-07-14 WO disclosed
EP-3042645-A1 Dental composites with improved storage stability Ivoclar Vivadent AG (LI) 2016-07-13 EP disclosed
EP-3034520-A1 Reaction resin composition and its use HILTI Aktiengesellschaft (LI) 2016-06-22 EP disclosed
EP-2824155-A1 Reaction resin composition and its use HILTI Aktiengesellschaft (LI) 2015-01-14 EP disclosed
US-7863396-B2 Silicon compounds CHISSO CORPORATION (JP) 2011-01-04 US disclosed
US-7687593-B2 Fluorinated polymer and polymer composition CHISSO CORPORATION (JP) 2010-03-30 US disclosed
US-7375170-B2 Organosilicon compound CHISSO CORPORATION (JP) 2008-05-20 US disclosed
US-20070135602-A1 Fluorinated polymer and polymer composition CHISSO CORPORATION 2007-06-14 US disclosed
US-20060287454-A1 Silicon compounds JNC CORPORATION (JP) 2006-12-21 US disclosed
US-20060175684-A1 Organosilicon compound JNC PETROCHEMICAL CORPORATION (JP) 2006-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060287454-A1 Silicon compounds H1-0, SPTBN1, SPTAN1 TBXAS1 3146/4885TET2 2483/4885POLB 1348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.