Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16299716 | 0.81 | — | — | |
| SCHEMBL18614651 | 0.73 | TRPA1 (0.36) | — | |
| SCHEMBL10073518 | 0.70 | TP53 (0.38) | ALDH1A1TSHR | |
| SCHEMBL713354 | 0.70 | TP53 (0.38) | ALDH1A1TSHR | |
| SCHEMBL3454958 | 0.70 | TP53 (0.38) | ALDH1A1TSHR | |
| SCHEMBL3454962 | 0.70 | TP53 (0.38) | ALDH1A1TSHR | |
| SCHEMBL713352 | 0.70 | TP53 (0.38) | ALDH1A1TSHR | |
| SCHEMBL713353 | 0.70 | TP53 (0.38) | ALDH1A1TSHR | |
| SCHEMBL18614656 | 0.69 | TYR (0.41) | ALDH1A1TSHR | |
| SCHEMBL18614665 | 0.68 | TYR (0.43) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124794-B2 | Method for the asymmetric synthesis of beta-lactone compounds | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-02-28 | — | — | US | disclosed |
| US-7728153-B2 | Method for the asymmetric synthesis of beta-lactone compounds | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-01 | — | — | US | disclosed |