Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21052387 | 0.89 | CA2 (0.50) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL14616914 | 0.87 | ALDH1A1 (0.48) | MEN1KMT2ANPC1CPB2ALDH1A1 | |
| SCHEMBL13575662 | 0.80 | CA2 (0.52) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL5679114 | 0.80 | CA2 (0.52) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL17617131 | 0.80 | CA2 (0.52) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL7530179 | 0.80 | GABRR1 (0.50) | MEN1KMT2ANPC1ALDH1A1CYP3A4 | |
| SCHEMBL7843927 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2ANPC1ALDH1A1CYP3A4 | |
| SCHEMBL29019883 | 0.80 | CA1 (0.44) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL284647 | 0.79 | ALDH1A1 (0.50) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL9609802 | 0.79 | CYP3A4 (0.44) | CA1CA2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310395-B1 | 9-SUBSTITUTED-B-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS | VETOQUINOL SA (FR) | 2012-01-18 | — | — | EP | disclosed |