Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.52 |
| ▸ | CASP6 | P55212 | 20/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 20/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073965 | 0.91 | CASP3 (0.50) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL627392 | 0.91 | CASP3 (0.50) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL10073769 | 0.91 | CASP3 (0.51) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL626605 | 0.90 | CASP3 (0.51) | CASP3CASP6CASP8 | |
| SCHEMBL627324 | 0.85 | CASP3 (0.71) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL10073964 | 0.85 | CASP3 (0.71) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL10074260 | 0.81 | CASP3 (0.61) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL625910 | 0.81 | CTSD (0.44) | CASP3CASP6CASP8 | |
| SCHEMBL10073352 | 0.81 | CTSD (0.44) | CASP3CASP6CASP8 | |
| SCHEMBL4434235 | 0.81 | CTSD (0.44) | CASP3CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021800-A2 | CASPASE INHIBITORS AS THERAPEUTICS FOR NEURAL AND ORGAN INJURY AND IMAGING | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |