Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3232102 | 0.91 | MIF (0.38) | MIFEGFRTP53PDCD1CD274 | |
| SCHEMBL2755028 | 0.72 | TYR (0.34) | ALDH1A1KDM4EGAARARARARG | |
| SCHEMBL677785 | 0.71 | ESR2 (0.42) | ALOX5RARARARGRARB | |
| SCHEMBL4408650 | 0.68 | RARA (0.40) | GAARARARARGRARBHDAC6 | |
| SCHEMBL28055648 | 0.66 | CA12 (0.57) | MIFEGFRTP53ALDH1A1KDM4E | |
| SCHEMBL2755031 | 0.65 | CYP1A2 (0.43) | TSHRPDCD1CD274MAPK1 | |
| SCHEMBL6240662 | 0.65 | TSHR (0.55) | KDM4ETSHRHSD17B10MAPT | |
| SCHEMBL2755032 | 0.65 | ALOX5 (0.40) | ALOX5ALDH1A1KDM4EGAAHSD17B10 | |
| Idronoxil SCHEMBL149612 | 0.64 | ESR2 (0.49) | MIFRARARARGRARB | |
| Idronoxil SCHEMBL29353213 | 0.64 | ESR2 (0.49) | MIFRARARARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120003270-A1 | 6-SUBSTITUTED ISOFLAVONOID COMPOUNDS AND USES THEREOF | MARSHALL EDWARDS, INC. | 2012-01-05 | — | — | US | disclosed |
| WO-2010012037-A1 | 6-SUBSTITUTED ISOFLAVONOID COMPOUNDS AND USES THEREOF | NOVOGEN RESEARCH PTY LTD (AU) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120003270-A1 | 6-SUBSTITUTED ISOFLAVONOID COMPOUNDS AND USES THEREOF | UGT1A6, CYP19A1, HSD17B11 | MIF 2077/4885EGFR 459/4885ALOX5 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.