Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 5/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 4/20 | 0.34 |
| ▸ | RARG | P13631 | 4/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073585 | 0.91 | MIF (0.37) | MIFHDAC6EGFRRARARARG | |
| SCHEMBL2755025 | 0.75 | KDM4E (0.42) | NR1H4RARARARGRARBMEN1 | |
| SCHEMBL677785 | 0.73 | ESR2 (0.42) | NR1H4RARARARGRARBESR1 | |
| SCHEMBL4408650 | 0.73 | RARA (0.40) | HDAC6NR1H4RARARARGRARB | |
| SCHEMBL2755028 | 0.72 | TYR (0.34) | NR1H4RARARARGRARBMEN1 | |
| SCHEMBL2755032 | 0.69 | ALOX5 (0.40) | NR1H4MTNR1AMEN1KMT2AMAPT | |
| SCHEMBL5962012 | 0.68 | ALOX12 (0.45) | NR1H4RARARARGMTNR1ARARB | |
| SCHEMBL2755031 | 0.67 | CYP1A2 (0.43) | PDCD1CD274 | |
| Idronoxil SCHEMBL149612 | 0.66 | ESR2 (0.49) | MIFNR1H4RARARARGRARB | |
| Idronoxil SCHEMBL29353213 | 0.66 | ESR2 (0.49) | MIFNR1H4RARARARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120003270-A1 | 6-SUBSTITUTED ISOFLAVONOID COMPOUNDS AND USES THEREOF | MARSHALL EDWARDS, INC. | 2012-01-05 | — | — | US | disclosed |
| WO-2010012037-A1 | 6-SUBSTITUTED ISOFLAVONOID COMPOUNDS AND USES THEREOF | NOVOGEN RESEARCH PTY LTD (AU) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120003270-A1 | 6-SUBSTITUTED ISOFLAVONOID COMPOUNDS AND USES THEREOF | UGT1A6, CYP19A1, HSD17B11 | MIF 2077/4885HDAC6 1560/4885NR1H4 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.