Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265774 | 0.83 | CYP3A4 (0.66) | CTBP2L3MBTL1TDP1CYP3A4CYP2C9 | |
| SCHEMBL7923429 | 0.83 | CYP3A4 (0.66) | CTBP2L3MBTL1TDP1CYP3A4CYP2C9 | |
| SCHEMBL367454 | 0.83 | CYP3A4 (0.66) | CTBP2L3MBTL1TDP1CYP3A4CYP2C9 | |
| SCHEMBL10073603 | 0.82 | CTBP2 (0.53) | CTBP2L3MBTL1TDP1CYP3A4CYP2C9 | |
| SCHEMBL12516012 | 0.78 | CTBP2 (0.59) | CTBP2L3MBTL1CYP3A4CYP2C9NPC1 | |
| SCHEMBL5790520 | 0.77 | CTBP2 (0.60) | CTBP2L3MBTL1TDP1CYP3A4RAB9A | |
| SCHEMBL24050328 | 0.77 | CTBP2 (0.40) | CTBP2L3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL92022 | 0.76 | CA2 (0.62) | CTBP2L3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL2525145 | 0.76 | CA2 (0.62) | CTBP2L3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL25245512 | 0.75 | CTBP2 (0.58) | CTBP2L3MBTL1TDP1CYP3A4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093274-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-10 | — | — | US | disclosed |
| US-20110178138-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-21 | — | — | US | disclosed |
| US-20100063114-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063114-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | GGT1, FNTA, FNTB | CTBP2 2175/4885L3MBTL1 1122/4885TDP1 1406/4885 |
| US-20110178138-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | RABGGTA, FNTA, RABGGTB | CTBP2 1088/4885L3MBTL1 1203/4885TDP1 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.