Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822122 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ACES2CES1 | |
| SCHEMBL12352210 | 0.78 | PGR (0.50) | ALDH1A1CES2CES1TSHRHSD17B3 | |
| SCHEMBL11515226 | 0.77 | NPC1 (0.53) | ALDH1A1MEN1KMT2ACES2CES1 | |
| SCHEMBL26614645 | 0.77 | NPC1 (0.53) | ALDH1A1MEN1KMT2ACES2CES1 | |
| SCHEMBL26614476 | 0.77 | NPC1 (0.53) | ALDH1A1MEN1KMT2ACES2CES1 | |
| SCHEMBL4130517 | 0.77 | NPC1 (0.53) | ALDH1A1MEN1KMT2ACES2CES1 | |
| SCHEMBL10407826 | 0.77 | NPC1 (0.53) | ALDH1A1MEN1KMT2ACES2CES1 | |
| SCHEMBL11559347 | 0.76 | HDAC1 (0.42) | ALDH1A1MAPTHPGDHSD17B3 | |
| SCHEMBL27351408 | 0.75 | CES2 (0.50) | ALDH1A1KMT2ACES2CES1KDM4E | |
| SCHEMBL4144101 | 0.73 | LTB4R2 (0.52) | ALDH1A1MEN1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120018685-A1 | Optical film, retardation film, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2012-01-26 | — | — | US | disclosed |