SCHEMBL10073747

SCHEMBL10073747

COc1ccc(Nc2nc(Nc3ccccc3)nc(Nc3ccccc3)n2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 4/20 0.77
MAPT P10636 4/20 0.71
KMT2A Q03164 4/20 0.71
MEN1 O00255 3/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
GAA P10253 2/20 0.71
L3MBTL1 Q9Y468 2/20 0.71
NPY5R Q15761 1/20 0.69
MAPK1 P28482 3/20 0.67
NPC1 O15118 3/20 0.67
RAB9A P51151 3/20 0.67
ALDH1A1 P00352 2/20 0.67
TP53 P04637 1/20 0.67
MERTK Q12866 3/20 0.63
LMNA P02545 1/20 0.63
KDM1A O60341 1/20 0.60
POLB P06746 1/20 0.60
RAD52 P43351 1/20 0.60
GFER P55789 1/20 0.60
ADORA2A P29274 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10099686 1.00 KCNH3 (0.77) KCNH3MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL12732285 0.93 KCNH3 (0.68) KCNH3MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL11812041 0.92 MAPT (0.81) KCNH3MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL3502169 0.92 MAPT (0.87) KCNH3MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL4544829 0.86 KCNH3 (0.68) KCNH3MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL9479393 0.86 RAB9A (0.81) KCNH3MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL316390 0.86 RAB9A (0.81) KCNH3MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL3289406 0.85 KCNH3 (0.69) KCNH3MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL4544853 0.85 MAPT (0.71) KCNH3MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL4544861 0.84 KCNH3 (0.70) KCNH3MAPTKMT2AMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120231217-A1 OPTICAL FILM, PHASE DIFFERENCE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-20120231217-A1 OPTICAL FILM, PHASE DIFFERENCE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-8147638-B2 Polarizing plate and display using the same KONICA MINOLTA OPTO INC. (JP) 2012-04-03 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-7981489-B2 Optical compensation sheet and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-7981489-B2 Optical compensation sheet and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-20110155306-A1 POLARIZING PLATE AND DISPLAY USING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2011-06-30 US disclosed
US-7968019-B2 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-06-28 US disclosed
US-7939002-B2 Retardation film, method for producing the same, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-10 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070134446-A1 Retardation film, method for producing the same, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. 2007-06-14 US disclosed
US-20070134446-A1 Retardation film, method for producing the same, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. 2007-06-14 US disclosed
US-20070097302-A1 RETARDATION FILM, POLARIZING PLATE AND VERTICAL ALIGNMENT MODE LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-05-03 US disclosed
US-20070097302-A1 RETARDATION FILM, POLARIZING PLATE AND VERTICAL ALIGNMENT MODE LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-05-03 US disclosed
US-20070019133-A1 Polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2007-01-25 US disclosed
US-20070019133-A1 Polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2007-01-25 US disclosed
US-7166339-B1 Phase contrast plate comprising one sheet of cellulose ester film containing aromatic compound FUJIFILM CORPORATION (JP) 2007-01-23 US disclosed
US-7166339-B1 Phase contrast plate comprising one sheet of cellulose ester film containing aromatic compound FUJIFILM CORPORATION (JP) 2007-01-23 US disclosed