SCHEMBL4544829

SCHEMBL4544829

COc1ccc(Nc2nc(Nc3cccc(OC)c3)nc(Nc3cccc(OC)c3)n2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 5/20 0.68
MEN1 O00255 3/20 0.66
KMT2A Q03164 3/20 0.66
NPC1 O15118 2/20 0.66
RAB9A P51151 2/20 0.66
MAPT P10636 2/20 0.63
GAA P10253 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
PIK3CA P42336 1/20 0.62
PIK3CB P42338 1/20 0.62
PIK3CG P48736 1/20 0.62
APP P05067 2/20 0.61
EGFR P00533 1/20 0.60
MAPK1 P28482 1/20 0.58
GALR2 O43603 2/20 0.58
GALR1 P47211 2/20 0.58
POLB P06746 1/20 0.57
SYK P43405 1/20 0.56
MTNR1A P48039 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544861 0.92 KCNH3 (0.70) KCNH3MEN1KMT2ANPC1RAB9A
SCHEMBL4544834 0.92 KCNH3 (0.70) KCNH3MEN1KMT2ANPC1RAB9A
SCHEMBL14583170 0.91 KCNH3 (0.59) KCNH3MEN1KMT2ANPC1RAB9A
SCHEMBL4544832 0.90 KCNH3 (0.65) KCNH3MEN1KMT2ANPC1RAB9A
SCHEMBL4547558 0.88 KCNH3 (0.55) KCNH3MEN1KMT2ANPC1RAB9A
SCHEMBL2112594 0.88 KMT2A (0.71) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL30741242 0.88 KMT2A (0.71) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL30741237 0.88 KMT2A (0.71) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL824521 0.87 MAPT (0.59) KCNH3MEN1KMT2ANPC1RAB9A
SCHEMBL4544846 0.87 MAPT (0.59) KCNH3MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9223070-B2 Optical film, polarizing plate equipped with the optical film, process for manufacture of the polarizing plate, and liquid crystal display device Konica Minolta, Inc. (JP) 2015-12-29 US disclosed
US-20150253480-A1 RETARDATION FILM, ELONGATED CIRCULARLY POLARIZING PLATE AND ORGANIC EL DISPLAY PRODUCED USING SAID RETARDATION FILM Konica Minolta, Inc. (JP) 2015-09-10 US disclosed
US-9110243-B2 Laminate film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-08-18 US disclosed
US-9103988-B2 Liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-08-11 US disclosed
US-8976325-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-03-10 US disclosed
US-8947621-B2 Liquid crystal display device comprising a front plate having a lamda/4 plate that includes a hard coat layer and method for manufacturing the same KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2015-02-03 US disclosed
US-8681295-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-03-25 US disclosed
US-20130293812-A1 OPTICAL FILM, POLARIZING PLATE EQUIPPED WITH THE OPTICAL FILM, PROCESS FOR MANUFACTURE OF THE POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2013-11-07 US disclosed
US-20120251781-A1 LAMINATE FILM, OPTICALLY COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-04 US disclosed
US-20120229734-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-20080213511-A1 Optical compensation film, process for producing optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-09-04 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080198303-A1 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed