Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY2A | P04746 | 2/20 | 0.53 |
| ▸ | TYR | P14679 | 4/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.44 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27416662 | 1.00 | AMY2A (0.53) | AMY2ATYRAMY1ALGALS3LGALS8 | |
| SCHEMBL16234072 | 0.94 | AMY2A (0.45) | AMY2ATYRAMY1ALGALS8MGAM | |
| SCHEMBL13716367 | 0.94 | AMY2A (0.45) | AMY2ATYRAMY1ALGALS8MGAM | |
| SCHEMBL15958439 | 0.93 | AMY2A (0.47) | AMY2ATYRAMY1ALGALS3LGALS8 | |
| SCHEMBL10047647 | 0.91 | TYR (0.48) | AMY2ATYRAMY1ALGALS3LGALS8 | |
| SCHEMBL17341181 | 0.91 | TYR (0.48) | AMY2ATYRAMY1ALGALS3LGALS8 | |
| SCHEMBL12902015 | 0.90 | TYR (0.56) | AMY2ATYRAMY1ALGALS3LGALS8 | |
| SCHEMBL12563490 | 0.90 | TYR (0.56) | AMY2ATYRAMY1ALGALS3LGALS8 | |
| SCHEMBL12604931 | 0.90 | TYR (0.56) | AMY2ATYRAMY1ALGALS3LGALS8 | |
| SCHEMBL12901988 | 0.90 | TYR (0.56) | AMY2ATYRAMY1ALGALS3LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120052107-A9 | HYDROPHOBIC POLYSACCHARIDES WITH PENDENT GROUPS HAVING TERMINAL REACTIVE FUNCTIONALITIES AND MEDICAL USES THEREOF | SURMODICS MD, LLC | 2012-03-01 | — | — | US | disclosed |
| US-20110159067-A1 | HYDROPHOBIC POLYSACCHARIDES WITH PENDENT GROUPS HAVING TERMINAL REACTIVE FUNCTIONALITIES AND MEDICAL USES THEREOF | SURMODICS, INC. | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052107-A9 | HYDROPHOBIC POLYSACCHARIDES WITH PENDENT GROUPS HAVING TERMINAL REACTIVE FUNCTIONALITIES AND MEDICAL USES THEREOF | CD44, FUT6, FUT5 | AMY2A 1526/4885TYR 506/4885AMY1A 720/4885 |
| US-20110159067-A1 | HYDROPHOBIC POLYSACCHARIDES WITH PENDENT GROUPS HAVING TERMINAL REACTIVE FUNCTIONALITIES AND MEDICAL USES THEREOF | CD44, FUT6, FUT5 | AMY2A 1526/4885TYR 506/4885AMY1A 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.