Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 7/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 6/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1629461 | 0.79 | SIGMAR1 (0.44) | ACACBSIGMAR1FFAR2AKT1RPS6KB1 | |
| SCHEMBL1627372 | 0.74 | HTT (0.43) | AKT2 | |
| SCHEMBL83976 | 0.74 | ACACB (0.40) | ACACBSIGMAR1FFAR2 | |
| SCHEMBL10077250 | 0.73 | HTT (0.45) | SIGMAR1AKT2 | |
| SCHEMBL16190534 | 0.73 | ACACB (0.46) | ACACBSIGMAR1 | |
| SCHEMBL12641308 | 0.70 | MAP2K7 (0.35) | ACACB | |
| SCHEMBL13312711 | 0.70 | EGLN2 (0.39) | ACACBSIGMAR1FFAR2 | |
| SCHEMBL82711 | 0.67 | SIGMAR1 (0.37) | ACACBSIGMAR1FFAR2 | |
| SCHEMBL31751063 | 0.66 | TTR (0.33) | ACACBRPS6KB1 | |
| SCHEMBL24204557 | 0.62 | FFAR4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299245-B2 | Method for producing pyrimidine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-30 | — | — | US | disclosed |
| US-8101753-B2 | Production method of pyrimidine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| US-7732448-B2 | Pyrimidine compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20090111984-A1 | Novel Method For Producing Pyrimidine Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20080039445-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111984-A1 | Novel Method For Producing Pyrimidine Compound | DPYD, UMPS, TYMP | ACACB 2155/4885SIGMAR1 4023/4885FFAR2 3559/4885 |
| US-20080039445-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | DPYD, DHFR, DHODH | ACACB 426/4885SIGMAR1 2950/4885FFAR2 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.