Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 4/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258698 | 0.82 | MGLL (0.56) | ALDH1A1HPGDRECQLBLMHTT | |
| SCHEMBL19019643 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KMT2APOLBTDP1HTT | |
| SCHEMBL259873 | 0.77 | MGLL (0.59) | ALDH1A1HPGDRECQLBLMHTT | |
| SCHEMBL21168596 | 0.73 | ALDH1A1 (0.61) | ALDH1A1KMT2AHPGDRECQLMEN1 | |
| SCHEMBL3677233 | 0.72 | MGLL (0.50) | ALDH1A1HPGDRECQLBLMHTT | |
| SCHEMBL13606476 | 0.72 | SMN1; SMN2 (0.50) | ALDH1A1KMT2AHPGDRECQLMEN1 | |
| SCHEMBL17532418 | 0.71 | ALDH1A1 (0.57) | ALDH1A1KMT2AHPGDRECQLMEN1 | |
| SCHEMBL11860195 | 0.71 | ALDH1A1 (0.50) | ALDH1A1KMT2AHPGDRECQLMEN1 | |
| SCHEMBL23430428 | 0.69 | MGLL (0.33) | ALDH1A1HPGDRECQLBLMHTT | |
| SCHEMBL19019377 | 0.69 | MGLL (0.56) | ALDH1A1KMT2AHPGDRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120049106-A1 | MALEIMIDE-FUNCTIONAL MONOMERS IN AMORPHOUS FORM | DESIGNER MOLECULES, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120049106-A1 | MALEIMIDE-FUNCTIONAL MONOMERS IN AMORPHOUS FORM | DESIGNER MOLECULES, INC. (US) | 2012-03-01 | — | — | US | disclosed |