Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.79 |
| ▸ | AKR1B10 | O60218 | 6/20 | 0.78 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.78 |
| ▸ | CA12 | O43570 | 3/20 | 0.78 |
| ▸ | CA7 | P43166 | 3/20 | 0.78 |
| ▸ | CA9 | Q16790 | 3/20 | 0.78 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.78 |
| ▸ | CA4 | P22748 | 2/20 | 0.78 |
| ▸ | CA6 | P23280 | 2/20 | 0.78 |
| ▸ | CA5A | P35218 | 2/20 | 0.78 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.78 |
| ▸ | TTR | P02766 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192951 | 1.00 | LMNA (0.79) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL13552179 | 0.92 | LMNA (0.93) | LMNAAKR1B10AKR1B1CA12CA7 | |
| Benzyl Cinnamate SCHEMBL901152 | 0.89 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| Benzyl Cinnamate SCHEMBL1871854 | 0.89 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| Benzyl Cinnamate SCHEMBL43212 | 0.89 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| Benzyl Cinnamate SCHEMBL43213 | 0.89 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL28388377 | 0.88 | LMNA (0.79) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL29087463 | 0.88 | CA12 (0.73) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL4501587 | 0.88 | AKR1B10 (1.00) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL22071063 | 0.88 | LMNA (0.84) | LMNAAKR1B10AKR1B1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024419-A2 | BRADYKININ RECEPTOR AGONISTS AND USES THEREOF TO TREAT OCULAR HYPERTENSION AND GLAUCOMA | ALCON RESEARCH, LTD. (US) | 2012-02-23 | — | — | WO | disclosed |