Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 11/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913612 | 0.89 | PREP (0.50) | PREPITGB3ITGA2BTGM2HDAC1 | |
| SCHEMBL4906556 | 0.86 | ITGB3 (0.56) | PREPITGB3ITGA2BTGM2DPP7 | |
| SCHEMBL10074274 | 0.86 | ITGB3 (0.56) | PREPITGB3ITGA2BTGM2DPP7 | |
| SCHEMBL4913602 | 0.84 | DPP7 (0.54) | PREPITGB3ITGA2BDPP7DPP4 | |
| SCHEMBL6100302 | 0.81 | PREP (0.53) | PREPITGB3ITGA2BDPP7DPP4 | |
| SCHEMBL27586353 | 0.81 | PREP (0.57) | PREPITGB3ITGA2BHDAC8CTSK | |
| SCHEMBL5351068 | 0.81 | PREP (0.57) | PREPITGB3ITGA2BHDAC8CTSK | |
| SCHEMBL10054472 | 0.80 | DPP4 (0.44) | PREPITGB3ITGA2BTGM2CTSK | |
| SCHEMBL6100308 | 0.80 | PREP (0.52) | PREPITGB3ITGA2BDPP7DPP4 | |
| SCHEMBL5871953 | 0.79 | TGM2 (0.44) | PREPITGB3ITGA2BTGM2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716843-B2 | INHIBITOR OF DIPEPTIDYL-PEPTIDASE IV | LES LABORATOIRES SERVIER (FR) | 2004-04-06 | — | — | US | disclosed |
| US-20030087950-A1 | New alpha-amino acid sulphonyl compounds | LES LABORATOIRES SERVIER (FR) | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087950-A1 | New alpha-amino acid sulphonyl compounds | DNPEP, DPP4, DPP7 | PREP 47/4885ITGB3 2050/4885ITGA2B 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.