Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 14/20 | 0.49 |
| ▸ | USP7 | Q93009 | 6/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | USP47 | Q96K76 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074358 | 0.88 | USP8 (0.51) | USP8USP7ERBB2KDM4EHPGD | |
| SCHEMBL10074360 | 0.77 | USP8 (0.42) | USP8USP7USP47 | |
| SCHEMBL10074703 | 0.76 | USP8 (0.47) | USP8USP7ERBB2KDM4EHPGD | |
| SCHEMBL10075452 | 0.74 | USP8 (0.60) | USP8USP7USP47 | |
| SCHEMBL2681245 | 0.73 | ERBB2 (0.61) | USP8USP7ERBB2KDM4EHPGD | |
| SCHEMBL10075460 | 0.69 | USP8 (0.40) | USP8USP7USP47 | |
| SCHEMBL10075465 | 0.68 | USP8 (0.52) | USP8USP7USP47 | |
| SCHEMBL10074715 | 0.68 | USP8 (0.50) | USP8USP7ERBB2KDM4EHPGD | |
| SCHEMBL11092179 | 0.66 | L3MBTL1 (0.54) | USP8USP7ERBB2KDM4EHPGD | |
| SCHEMBL4684019 | 0.66 | ERBB2 (0.53) | USP8USP7ERBB2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119828-B2 | Material for an organic electroluminescence device and an organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20100044686-A1 | MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100044686-A1 | MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE | AFF4, KCNH3, HCN4 | USP8 4307/4885USP7 4265/4885ERBB2 3050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.