SCHEMBL10074384

SCHEMBL10074384

N#Cc1c2ccccc2c(C#N)c2cc(C=Cc3ccc(N(c4ccccc4)c4ccc(C=O)cc4)cc3)ccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.38
ALDH1A1 P00352 5/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
CTNNB1 P35222 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
KDM4E B2RXH2 2/20 0.33
RELA Q04206 1/20 0.33
ALDH3A1 P30838 1/20 0.33
ALDH1A3 P47895 1/20 0.33
KIF11 P52732 2/20 0.33
CYP2A6 P11509 2/20 0.33
USP20 Q9Y2K6 1/20 0.32
IP6K1 Q92551 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14569512 0.92 APP (0.40) APPALDH1A1L3MBTL1MEN1USP2
SCHEMBL10074381 0.87 APP (0.41) APPALDH1A1L3MBTL1MEN1USP2
SCHEMBL12091216 0.87 APP (0.39) APPALDH1A1MEN1USP2MAPT
SCHEMBL12091217 0.87 APP (0.35) APPALDH1A1L3MBTL1MEN1USP2
SCHEMBL10074382 0.86 S100A4 (0.32) APPALDH1A1L3MBTL1MEN1USP2
SCHEMBL14569509 0.86 APP (0.39) APPALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL14569482 0.86 RELA (0.51) APPALDH1A1L3MBTL1MEN1MAPT
SCHEMBL14079455 0.85 APP (0.41) APPALDH1A1L3MBTL1MEN1USP2
SCHEMBL14079459 0.85 APP (0.38) APPALDH1A1L3MBTL1KDM4ERELA
SCHEMBL12309967 0.84 TRPA1 (0.47) APPKDM4ERELASLC16A3SLC16A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8207088-B2 Transfer substrate and method for fabricating organic electroluminescent element SONY CORPORATION (JP) 2012-06-26 US disclosed
US-20090045735-A1 TRANSFER SUBSTRATE AND METHOD FOR FABRICATING ORGANIC ELECTROLUMINESCENT ELEMENT SONY CORPORATION (JP) 2009-02-19 US disclosed
US-20080164809-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-07-10 US disclosed