Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.41 |
| ▸ | SCN2B | O60939 | 1/20 | 0.41 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2626898 | 0.87 | SCN9A (0.43) | SCN9ASCN2BSCN1BKAT6ASCN5A | |
| SCHEMBL2626901 | 0.85 | SCN2B (0.42) | SCN9ASCN2BSCN1BKAT6APTGS1 | |
| SCHEMBL2632994 | 0.81 | SCN9A (0.59) | SCN9ASCN2BSCN1BSCN5ARIPK2 | |
| SCHEMBL2119193 | 0.80 | PRMT5 (0.46) | SCN9ASCN2BSCN1BPTGS1PTGS2 | |
| SCHEMBL2626897 | 0.80 | PTGS2 (0.56) | KAT6APTGS1PTGS2 | |
| SCHEMBL10182013 | 0.79 | NTRK1 (0.40) | SCN9APTGS1PTGS2RIPK2 | |
| SCHEMBL2689196 | 0.67 | ELOVL1 (0.41) | — | |
| SCHEMBL15018194 | 0.66 | HTR7 (0.49) | SCN9ASCN5APTGS2NPC1HTR7 | |
| SCHEMBL253887 | 0.66 | IRAK4 (0.40) | SCN9ASCN2BSCN1BKAT6ASCN5A | |
| SCHEMBL253139 | 0.66 | RIPK2 (0.38) | SCN9ASCN2BSCN1BSCN5ARIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558458-B1 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER IP GMBH (DE) | 2017-09-06 | — | — | EP | disclosed |
| US-9339032-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-17 | — | — | US | disclosed |
| US-20140135346-A1 | Novel Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-05-15 | — | — | US | disclosed |
| US-8664229-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2014-03-04 | — | — | US | disclosed |
| US-20120095023-A1 | Novel Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| WO-2011128304-A2 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135346-A1 | Novel Heterocyclic Compounds as Pesticides | DDT, PTMS, AADAC | SCN9A 2271/4885SCN2B 1293/4885SCN1B 1940/4885 |
| US-20120095023-A1 | Novel Heterocyclic Compounds as Pesticides | DDT, PTMS, AADAC | SCN9A 2271/4885SCN2B 1293/4885SCN1B 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.