Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 7/20 | 0.39 |
| ▸ | DRD4 | P21917 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13450065 | 0.98 | KMT2A (0.45) | POLBKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15247872 | 0.98 | KMT2A (0.45) | POLBKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13154688 | 0.92 | TSHR (0.41) | POLBKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25446979 | 0.86 | KMT2A (0.38) | POLBKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL861034 | 0.85 | KMT2A (0.57) | KMT2ACYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL18622113 | 0.85 | POLB (0.57) | POLBKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22821556 | 0.83 | KMT2A (0.55) | POLBKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17777241 | 0.83 | ALDH1A1 (0.58) | KMT2ACYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL23839910 | 0.83 | ALDH1A1 (0.58) | KMT2ACYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10633351 | 0.83 | MEN1 (0.58) | POLBKMT2AALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689430-B2 | Insulin receptor partial agonists | MERCK SHARP & DOHME CORP. (US) | 2020-06-23 | — | — | US | disclosed |
| US-20190177393-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-06-13 | — | — | US | disclosed |
| US-8097688-B2 | Ink composition and inkjet recording method | FUJIFILM CORPORATION (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20100227076-A1 | INK COMPOSITION AND INKJET RECORDING METHOD | FUJIFILM CORPORATION (JP) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177393-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | POLB 3593/4885KMT2A 4174/4885CYP2D6 2972/4885 |
| US-10689430-B2 | Insulin receptor partial agonists | INSR, GPR119, IRS1 | POLB 3593/4885KMT2A 4174/4885CYP2D6 2972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.