SCHEMBL10074640

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8426868	0.84	MAP2K4 (0.37)	BRD4MAP2K4KDM1A
	SCHEMBL15687671	0.84	BRD4 (0.38)	BRD4ALDH1A1MAP2K4KDM4EHPGD
	SCHEMBL13794562	0.83	DYRK1A (0.44)	DYRK1ACNR2BRD4ALDH1A1STS
	SCHEMBL1940310	0.82	DYRK1A (0.39)	DYRK1ACNR2BRD4KDM4C
	SCHEMBL15578604	0.81	DYRK1A (0.39)	DYRK1ACNR2BRD4BACE1ALDH1A1
	SCHEMBL29588521	0.81	CHRM2 (0.43)	CNR2ALDH1A1MAP2K4ELANEKDM4E
	SCHEMBL3347471	0.81	CHRM2 (0.43)	CNR2ALDH1A1MAP2K4ELANEKDM4E
	SCHEMBL13794080	0.81	DYRK1A (0.37)	DYRK1ACNR2BRD4ALDH1A1STS
	SCHEMBL2922296	0.81	ELANE (0.41)	CNR2BRD4ALDH1A1ELANEMEN1
	SCHEMBL13793993	0.80	ALDH1A1 (0.41)	DYRK1ACNR2BRD4ALDH1A1STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.