Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 3/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435563 | 0.90 | PPARA (0.56) | PPARATRPM8CTRB1TACR1ITGB3 | |
| SCHEMBL10054485 | 0.90 | CYP3A4 (0.51) | NAAACYP3A4TRPM8MMP12MAPK1 | |
| SCHEMBL6350990 | 0.84 | TRPM8 (0.61) | TRPM8CTRB1TACR1ITGB3 | |
| SCHEMBL7414480 | 0.84 | TRPM8 (0.61) | TRPM8CTRB1TACR1ITGB3 | |
| SCHEMBL7418088 | 0.84 | TRPM8 (0.61) | TRPM8CTRB1TACR1ITGB3 | |
| SCHEMBL7430937 | 0.84 | TRPM8 (0.61) | TRPM8CTRB1TACR1ITGB3 | |
| SCHEMBL7245549 | 0.84 | TRPM8 (0.61) | TRPM8CTRB1TACR1ITGB3 | |
| SCHEMBL3798084 | 0.82 | CYP3A4 (0.52) | NAAACYP3A4MMP12CTRB1TACR1 | |
| SCHEMBL3798080 | 0.82 | CYP3A4 (0.52) | NAAACYP3A4MMP12CTRB1TACR1 | |
| SCHEMBL10054482 | 0.82 | NAAA (0.46) | NAAACYP3A4PPARATRPM8ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |