Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10075222 | 0.92 | RIPK1 (0.46) | RIPK1GPR119LIPEPIK3CAUSP2 | |
| SCHEMBL10070492 | 0.83 | RYR2 (0.46) | RIPK1PIK3CA | |
| SCHEMBL10070995 | 0.80 | RIPK1 (0.48) | RIPK1PIK3CAESR2 | |
| SCHEMBL807151 | 0.78 | RIPK1 (0.47) | RIPK1PIK3CAESR2 | |
| SCHEMBL10074955 | 0.78 | RIPK1 (0.47) | RIPK1PIK3CAESR2 | |
| SCHEMBL14023336 | 0.78 | RIPK1 (0.48) | RIPK1PIK3CAESR2 | |
| SCHEMBL4789461 | 0.78 | RIPK1 (0.43) | RIPK1SMN1; SMN2PRMT5WDR77 | |
| SCHEMBL19657617 | 0.76 | RIPK1 (0.64) | RIPK1GPR119PIK3CAUSP2SMN1; SMN2 | |
| SCHEMBL30405260 | 0.75 | RIPK1 (0.48) | RIPK1PIK3CAUSP2SMN1; SMN2ESR2 | |
| SCHEMBL13765601 | 0.75 | RIPK1 (0.48) | RIPK1GPR119PIK3CAUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019071-A1 | METHODS OF PREVENTING AND TREATING SARCOPENIA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-02-09 | — | — | WO | disclosed |