Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | TOP1 | P11387 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074696 | 0.91 | PIK3R1 (0.39) | PIK3R1PIK3CATOP1MAOBMAPT | |
| SCHEMBL10074697 | 0.91 | PIK3R1 (0.39) | PIK3R1PIK3CATOP1MAOBMAPT | |
| SCHEMBL10074361 | 0.88 | KDM4E (0.48) | MAPTSMN1; SMN2KDM4EMAPK8MAPK9 | |
| SCHEMBL10075462 | 0.87 | MYC (0.40) | TOP1MAOBJAK2ALDH1A1MYC | |
| SCHEMBL12247837 | 0.84 | KIF11 (0.40) | TOP1MAOBJAK2ALDH1A1MAPT | |
| SCHEMBL10074362 | 0.83 | USP8 (0.36) | PIK3R1PIK3CAMAPTSMN1; SMN2MAPK8 | |
| SCHEMBL10075003 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTSMN1; SMN2KDM4ECYP2C19 | |
| SCHEMBL10075448 | 0.81 | MEN1 (0.36) | MAOBMAPTSMN1; SMN2TDP1KDM4E | |
| SCHEMBL10050415 | 0.81 | PIK3R1 (0.42) | PIK3R1PIK3CATOP1MAOBJAK2 | |
| SCHEMBL12248174 | 0.80 | MYC (0.36) | TOP1MAOBJAK2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119828-B2 | Material for an organic electroluminescence device and an organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20100044686-A1 | MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100044686-A1 | MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE | AFF4, KCNH3, HCN4 | PIK3R1 4703/4885PIK3CA 4322/4885TOP1 3532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.