Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950830 | 0.75 | TYR (0.39) | APPKDM4EALDH1A1MAPTPKM | |
| SCHEMBL20865908 | 0.68 | ALDH1A1 (0.41) | APPKDM4EALDH1A1MAPTPKM | |
| SCHEMBL29954398 | 0.68 | ALDH1A1 (0.41) | APPKDM4EALDH1A1MAPTPKM | |
| SCHEMBL28470181 | 0.68 | ALDH1A1 (0.40) | APPALDH1A1TDP1BACE1TRIM24 | |
| SCHEMBL16359749 | 0.67 | ERN1 (0.42) | KDM4EALDH1A1MAPTPKMTDP1 | |
| SCHEMBL9140935 | 0.67 | TYR (0.44) | ALDH1A1MAPTTDP1GAAMEN1 | |
| SCHEMBL29951036 | 0.66 | SRC (0.44) | APPKDM4EALDH1A1MAPTPKM | |
| SCHEMBL6898737 | 0.66 | SRC (0.44) | APPKDM4EALDH1A1MAPTPKM | |
| SCHEMBL7913737 | 0.66 | TRIM24 (0.47) | KDM4EALDH1A1MAPTPKMTDP1 | |
| SCHEMBL29952866 | 0.66 | TRIM24 (0.47) | KDM4EALDH1A1MAPTPKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019071-A1 | METHODS OF PREVENTING AND TREATING SARCOPENIA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-02-09 | — | — | WO | disclosed |