Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 6/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954894 | 0.84 | TYR (0.43) | TYRTRIM24TRIM33BACE1ERN1 | |
| SCHEMBL19445596 | 0.76 | ALDH1A1 (0.36) | ALDH1A1KDM4EPOLBGAATDP1 | |
| SCHEMBL31050324 | 0.76 | ERN1 (0.52) | ERN1ALDH1A1 | |
| SCHEMBL7820970 | 0.76 | ERN1 (0.52) | ERN1ALDH1A1TDP1HPGDHSD17B10 | |
| SCHEMBL30033864 | 0.76 | ALDH1A1 (0.42) | ERN1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL7826405 | 0.76 | ALDH1A1 (0.42) | ERN1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL1017248 | 0.76 | ERN1 (0.52) | ERN1ALDH1A1 | |
| SCHEMBL10075211 | 0.75 | TMEM97 (0.37) | TYRTRIM24TRIM33BACE1ERN1 | |
| SCHEMBL28667906 | 0.75 | ALDH1A1 (0.45) | TYRTRIM24TRIM33ERN1ALDH1A1 | |
| SCHEMBL2481401 | 0.73 | HSD17B10 (0.36) | TYRESR1ESR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |